Vitamin A For Better Gut Health
Our gut microbiome plays an important role in keeping us healthy. Vitamin A has been shown to be a critical vitamin for gut health. The microbiome consists of microbes that are both helpful and potentially harmful. Most are symbiotic (where both the human body and microbiota benefit) and some, in smaller numbers, are pathogenic (promoting disease). In a healthy body, pathogenic and symbiotic microbiota coexist without problems.
But if there is a disturbance in that balance—brought on by infectious illnesses, certain diets, or the prolonged use of antibiotics or other bacteria-destroying medications—dysbiosis occurs, stopping these normal interactions. As a result, the body may become more susceptible to disease.The gut bacteria manage to do this by controlling the immune function by activating Vitamin A in the gastrointestinal tract.
Vitamin A provides a wide range of nutritional support for the entire body, including vision, skin and mucous membranes. Vitamin A is also an essential nutrient for the body’s natural defense systems.*
- Supports the body’s immune system*
- Promotes eye health*
- Helps with mucosal Tolerance
- Helps with Leaky gut
- Helps with SIgA levels
Vitamin A and Secretory IgA
When it comes to gut health Secretory IgA is something you want to learn more about. Secretory IgA (SIgA) is the principal immunoglobulin (Ig) on mucosal surfaces of humans and many other mammals. Globally, more IgA is produced than all other Ig isotypes combined. IgA is secreted into the gut lining and provides protection against harmful pathogens. It thus helps maintain a healthy flora. Retinoic acid, derived from vitamin A , exerts a positive impact on the precursors for IgA-producing plasma cell
Perhaps you have had some recent stool testing and your tests results showed problems with SIgA. What does it mean if your stool secretory IgA result is too high? well…..High levels of Secretory IgA might reflect an activated immune response to chronic infections including viral infections such as EBV (Epstein–Barr virus), CMV (Cytomegalovirus), HIV, and/ or inflammatory reactions. Vitamin A has been shown to help improve SIgA levels by supporting the immune system and the mucosal levels.
Vitamin A and Mucosal Tolerance
Vitamin A and Leaky Gut
Vitamin A cannot be synthesised by the human body; it must be absorbed by the intestine from the diet. In the presence of innate danger signals Vitamin A effects can diminish or synergise with innate responses to promote or enhance protective immunity, ensuring suitable plasticity.
The cells along the vast mucosal surfaces of your body are constantly in contact with foods, microbes and toxins. They make innumerable immunological decisions every day—so many that a single day’s encounters exceed that of the rest of your immune system over a lifetime. As the gut makes its decisions, it then relays information from the innate to the adaptive, systemic immune system. Mucosal tolerance is a necessity for us to survive; without it we would not survive a single day.
The gut is where health begins, and is also home to a huge microbiome made of innumerable species of bacteria. Vitamin A is the key to the gut making the right decisions
Overall Health: Vitamin A is a fat-soluble vitamin. It is required for vision, growth and bone development, reproductive function, cell growth, immune function, GI function including maintaining the integrity of the gut mucosal and epithelial surfaces.*
Vitamin A is sourced from cod liver oil and synthetic vitamin A palmitate. Natural tocopherols are derived from highly refined soybean oil.
Pure Encapsulations recommends 1 capsule daily, with a meal.
Not to be taken by pregnant or lactating women. Ongoing use should be monitored by a health professional. Chronic use of large amounts of vitamin A can cause symptoms of vitamin A toxicity including fatigue, irritability, depression, abdominal discomfort, nausea and vomiting, mild fever, dry skin, anemia or decreased white blood cells. Consult your physician for more information.
Vitamin A supplementation should be avoided by individuals taking retinoid medications. It may also be contra-indicated with blood thinning medications, tetracycline antibiotics and hepatotoxic medications. Consult your physician for more information.