Vital-Zymes Complete Chewable (180 caps)

Digestive Enzymes Health with Vital Zyme

Vital Zymes Complete Chewable is one of Dr Hagmeyer’s most recommended, multi-enzyme formulations.Vital Zymes Complete Chewable offers an unusually comprehensive range of plant/ microbial-based enzymes, together with lysozyme, that work in concert to support normal enzyme activities such as digestion of foods and intestinal repair and maintenance mechanisms.^† The broad-spectrum combination of enzymes in Vital-Zymes Complete supports the breakdown, absorption, and utilization of macronutrients from a wide spectrum of foods, including proteins and protein peptides, complex carbohydrates, disaccharides and sugars, lipids/fats, and vegetable fibers.^† As such, Vital-Zymes Complete is an important dietary adjunct for individuals who seek to improve nutrient uptake, and for those with occasional indigestion.^† It can also be used for individuals who wish to support a balanced microbiota and healthy inflammation metabolism.^†

About Vital-Zymes Complete

• Delivers a full complement of high-activity enzymes
• Contains highly purified enzymes to meet the needs of food-sensitive individuals
• Free of maltodextrin (wheat, rice, or corn-derived), commonly used as a base in enzyme raw materials
• Contains no porcine or other animal-derived enzymes
• Avoids fruit-derived enzymes (bromelain, papain, and kiwi) for improved tolerance by sensitive individuals
• Active across a broad range of pH conditions (pH of 2 to 10) for benefit throughout the entire intestinal tract
• Supplies a broad-spectrum of disaccharidases (lactase, maltase, sucrase/invertase, pullulanase, and isomaltase) to assist cleaving of sugars that may be fermented by organisms that shift the Assists protein breakdown, but avoids excessive amounts of proteases that may irritate GI tissues^†
• Dipeptidyl peptidase IV (DPP-IV) activity supports optimal cleaving of casein and gluten and their exorphin peptides (casomorphin and gluteomorphin)^†
• Supplies Serratia peptidase enzyme to support sensitive GI tissues from irritation and lysozyme for its unique lysing action on bacterial and yeast cell walls and broad immune support^†

Benefits of Vital Zymes Complete

Digestive enzymes break down food macronutrients, such as proteins, carbohydrates, and fats into smaller molecules for absorption by the intestines. These enzymes are secreted by salivary glands (alpha-amylase and lingual lipase), the stomach (pepsinogen, gelatinase, and gastric lipase), the pancreas (alpha-amylase, lipase, trypsinogen, and chymotrysinogen), and the small bowel (disaccharidases, intestinal lipase, and erepsin protease).

Digestive enzymes are also present in raw foods such as fresh fruits and vegetables. Enzymes in raw foods are thought to work synergistically with the body’s endogenous digestive enzymes to more completely digest food carbohydrates and other macronutrients.

This action is lost, however, when foods are cooked or heat processed, as this destroys the natural catalytic activity of food digestive enzymes.1 Enzyme supplementation supports healthy digestion and may therefore alleviate occasional abdominal discomfort, bloating, gas, indigestion, or loose stools while supporting nutrient absorption.† Incompletely digested food in the gut may putrefy and produce irritating substances that affect intestinal mucosal integrity and gut permeability, systemic immune function, and overall energy.

Children with dyspepsia typically exhibit low activity of duodenal maltase-glucoamylase and/or disaccharidases.2

Supplementing the diet with microbialderived digestive enzymes can assist the complete digestion of food components, promote normal nutrient absorption, and reduce the number of large, immunologically active molecules that can leak through the intestinal mucosa lining if permeability is not optimal.

How Digestive enzymes in Vital Zymes Complete work

Amylases (amylase, alpha-amylase, and glucoamylase) are glycoside hydrolases that cleave a-(1g4) glycosidic bonds. Amylases hydrolyze amylose and amylopectin found in starchy vegetables such as potatoes, corn, rice, and wheat as well as glycogen and other related carbohydrates.

Disaccharidases (lactase, sucrase/invertase, and maltase) are enzymes that primarily hydrolyze disaccharides into their component monosaccharides (single sugars). Disaccharidases are normally found in the small intestinal brush border and are critical for the final steps of carbohydrate digestion.3 Acid, alkaline, and neutral proteases are enzymes that hydrolyze proteins into smaller fragments known as polypeptides.

Peptidases are enzymes that break polypeptides down into their constituent amino acids. Absorption of the undigested proteins and polypeptides may trigger food hypersensitivities. Incomplete digestion of gluten and casein may result in the production of exorphin (exogenous opiate-like) polypeptides that have the capacity to cause or potentiate adverse neurological symptoms.

Vital-Zymes Complete and Vital-Zymes Chewable contain a full complement of protease and peptidase enzymes in amounts appropriate to support the breakdown of a wide spectrum of dietary proteins while avoiding excessive amounts of proteases found in some formulations that may irritate mucosal membranes. Protease/peptidase complex has endopeptidase, exopeptidase, and DPP-IV activity.

DPP-IV activity is critical to the catabolic inactivation of exorphins, bioactive peptides derived from food proteins with morphine-like opioid effects.4

Exorphins derive primarily from the milk protein casein, gluten, and soy. The DPP-IV activity present in the protease/peptidase provides for complete digestion of proline-rich proteins and efficient breakdown of dietary exorphins.†

Serratia peptidase is a unique endopeptidase enzyme that supports healthy inflammatory response during occasional GI stress by protecting sensitive gastrointestinal tissue from irritation and breaking down extraneous fibrin, mucus, and other compounds that accumulate as a part of the body’s natural repair process.†

Pullulanase, together with glucoamylase, supplies the isomaltase activity lacking in fungal- and microbial-derived sucrases facilitating the complete breakdown of highly branched amylopectin starch molecules. Cellulase denotes a family of enzymes that digest plant material and promote greater nutrient absorption. Phytase breaks down phytic acid, an anti-nutrient that would otherwise complex with dietary minerals and interfere with their absorption.†

Lipase converts dietary triglycerides (fats or lipids) into diglycerides, monoglycerides, fatty acids, and glycerol. Absorption of fatty acids is important for health, normal fat digestion and stool fat content, and absorption of fat-soluble nutrients such as vitamins A, D, E, and K. 5-7

The lipase in Vital-Zymes Complete and Vital-Zymes Chewable promotes healthy fat digestion and absorption of essential lipids and fat-soluble nutrients.†

Lysozyme (in Vital-Zymes Complete) is an enzyme found in tears, saliva, mucus, and breast milk. Lysozyme breaks down peptidoglycans found in bacterial cell walls especially those of Gram-positive bacteria.†