Pyloricil is formulated to support the health of the stomach lining and GI tract with unique ingredients that promote microbial balance against H.pylori. Pyloricil provides zinc carnosine, a zinc complex of L-carnosine approved in Japan since 1994 for its use in stomach health; mastic gum, traditionally used to protect the stomach lining and shown in studies to promote microbial balance; bismuth citrate, used to promote normal bacterial growth, and for its soothing action on the gastric and mucosal lining; and berberine sulfate, a compound with microbial-balancing properties.
- Promotes Healthy Microbial Balance in the GI Tract especially when H.pylori is present
- Helps Maintain Gastrointestinal Comfort
- Soothes the Stomach and GI Tract
The Centers for Disease Control and Prevention estimates that approximately two-thirds of the world’s population has stomach microbial balance concerns. While some will never experience discomfort, others may need support. Maintaining healthy microbial balance and a strong immune system is integral to optimal GI health, as well as overall health. In addition, since the body’s immune system is a complex and dynamic defense system, healthy microbial balance helps ensure optimal immune function. Research has shown that the natural ingredients in Pyloricil help with H.pylori infection and soothe the stomach lining and GI tract.
Mastic gum is a resinous product which is obtained from the stem and leaves of the mastic tree (Pistacia lentiscus). The mastic tree is an evergreen shrub native to the Mediterranean Basin and has historically been used to support the health of the stomach. In a double-blind study, 60 patients randomly assigned to receive mastic (1 g/ day), or placebo, for two weeks demonstrated that mastic gum supported the health of the stomach lining in 78% of the patients in the control group (versus 22% of those receiving placebo).1 Mastic gum has also been shown to promote healthy microbial balance in the GI tract.2
Bismuth citrate is a naturally occurring mineral, frequently used to soothe the gastric and mucosal linings.3 Bismuth citrate also promotes microbial balance in the GI tract.4 Bismuth citrate offers a key advantage when compared to other bacterial- balancing therapies. While it is very common for bacteria to develop a resistance to various bacterial-balancing agents, it is unlikely they will develop resistance to bismuth citrate.
Zinc carnosine has been approved in Japan since 1994 for its use in stomach health. The health-promoting effects of zinc are enhanced significantly when combined with the essential nutrient, carnosine. Japanese scientists have led the way in developing this zinc carnosine compound, which combines zinc and carnosine linked by a chemical bond. Research has demonstrated that zinc carnosine stabilizes the mucosal lining of the stomach and small intestines.
In a study examining the effects of zinc carnosine on animal digestive tracts, following exposure to indomethacin or to stress, this nutrient combination was shown to support gastric and intestinal health by stimulating the migration and growth of cells. In the human clinical trial based on the same model, 10 healthy volunteers consumed indomethacin (50 mg three times daily) along with placebo, or zinc carnosine. Indomethacin increased gut permeability (impaired barrier function of the gut’s lining) by a factor of three in the placebo group. As compared to the placebo group, the control group consuming zinc carnosine showed no increase at all in gut permeability.5
Berberine sulfate is a botanical extract found in the roots and barks of various plants including Oregon grape root (Berberis aquifolium), barberry (Berberis vulgaris) and goldenseal (Hydrastis canadensis).
Berberine has a long history of use in both Ayurvedic and Chinese medicine. Berberine sulfate has been shown to promote healthy microbial balance in the GI tract and maintain normal inflammatory balance throughout the body.6
1 capsule two times per day or as recommended by your health care professional.
Does Not Contain
Gluten, yeast, artificial colors and flavors.
Do not consume this product if you are pregnant or nursing. Consult your physician for further information.
1. Al-HabbalMJ,Al-HabbalZ,HuwezFU.Adouble-blinded controlled clinical trial of mastic and placebo in the treatment of duodenal ulcer. Clin Exp Pharmacol Physiol 1984; 11:541-544.
2. HuwezFU,ThirlwellD,CockaneA,Ala’AldeenDA.Mastic gum kills Helicobacter pylori. N Engl J Med 1998; 339:1946.
3. Cammarota,G.,Cannizzaro,O.etal.Five-dayregimens containing ranitidine bismuth citrate plus high-dose clarithromycin and either amoxycillin or tinidazole for Helicobacter pylori infection. Aliment Pharmacol Ther 2000; 14(1):73-77.
the treatment of Helicobacter pylori infection. Aliment Pharmacol Ther 1997; 11 Suppl 1:27-33.
5. MahmoodA,FitzGeraldAJ,MarchbankT,etal.Zinc carnosine, a health food supplement that stabilizes small bowel integrity and stimulates gut repair processes. Gut 2007 Feb;56(2):168-175.
6. Monograph: Berberine. Altern Med Rev 2000; 5(2); 175-177