Ortho Biotic® Women’s is a unique probiotic formula designed to maintain a healthy vaginal microflora and support urogenital health. A healthy vaginal environment is mildly acidic, and therefore Lactobacillus species dominate this ecosystem. Ortho Biotic® Women’s provides two specific species of Lactobacilli: L. reuteri and L. rhamnosus. These two species are backed by human clinical studies to establish a healthy, stable vaginal ecosystem.
Overview
Every area of the human body has a unique ecology and therefore a unique microbiome. The gut microbiome is spoken about frequently, but less commonly discussed are the specific microbiomes contained in other areas such as the skin, the lungs, the mouth, and even the vagina. The vaginal microbiome is abundant in Lactobacillus species, as they contribute heavily to the production of lactic acid.
The lactic acid maintains a pH of 4, which if elevated, is a risk for vaginal microbiome challenges. Urogenital concerns are experienced frequently by women, and the most common interventions do little to address the state of vaginal ecology, and therefore, repeated challenges are often experienced. Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 have been studied and proven to support healthy vaginal ecology and promote microbial balance.
Vagina Yeast Infections
An overgrowth of the fungus candida causes a vaginal yeast infection. A vaginal yeast infection causes the skin around your vagina to burn and itch, and it may change the consistency of your vaginal discharge. Traditional medicine includes anti-fungal medication. But this is really only a bandaid for woman with chronic Yeast infections. To really address the cause, we need to look at the reason why a yeast overgrowth exists in the first place. Certain factors make you more likely to get a vaginal yeast infection.
Certain factors can increase your risk of getting a vaginal yeast infection. Some of those are:
- Using Antifungals, antibiotics, birth control pills or certain steroids.
- Being pregnant.
- Woman taking hormone replacement therapy or Estrogen replacement
- Having a health condition that weakens your immune system.
- Having unmanaged diabetes.
- Hypothyroidism
- Brain fog, decline in memory, or cognitive dysfunction.
- Abdominal pain, stool changes, or excess gas and bloating.
- Chronic fatigue and sleep disturbances.
- Mood disturbances, depression, or anxiety.
- Frequent yeast infections
- Urinary Tract Infections
- Synthetic Hormones Like oral contraceptives, HRT or Estrogen replacement.
Probiotics in Vaginal Microbial Balance
Twelve to 50% of women worldwide experience vaginal microbiome challenges that significantly impact their quality of life.1,2,3 In several clinical studies, daily intake of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 were shown to promote the health of the vaginal microbiota. In another study, women with vaginal microbiome challenges were randomized to receive placebo or Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. After 6 weeks, significantly more women in the probiotic group maintained a balanced vaginal microbiota compared to women in the placebo group.4
A study of post-menopausal women with vaginal microbiome challenges were randomized to receive a placebo or Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. After four weeks, the women who received the probiotic blend maintained a healthy vaginal microbiota within the normal, beneficial range, whereas the balance of vaginal bacteria of the women in the placebo group was not significantly improved.1,5,6
Probiotics and Urogenital Health
Urinary tract microbiome challenges are very common, impacting 150 million people each year. The specific blend of probiotics in Ortho Biotic® Women’s has been associated with supporting vaginal and urinary tract health. Specifically, studies suggest these probiotics promote vaginal and urinary tract health when used alone or in combination with common interventions. In other studies, participants consuming this specific probiotic blend maintained a healthy urinary tract microbiota with fewer incidence of urinary tract challenges.7,8,9
Directions
1 capsule per day or as recommended by your health care professional.
Does Not Contain
Gluten, yeast, artificial colors or flavors.
Cautions
If you are pregnant or nursing, consult your physician before taking this product.
References
1. Bradshaw CS, et al. Prevalent and Incident Bacterial Vaginosis Are Associated with Sexual and Contraceptive Behaviours in Young Australian Women. PLoS One. 2013;8(3):e57688. (PubMed)
2. Allsworth JE, Peipert JF. Prevalence of bacterial vaginosis: 2001-2004 National Health and Nutrition Examination Survey data. Obstet Gynecol. 2007;109(1):114-20. (PubMed)
3. Chico RM, et al. Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review. JAMA. 2012;307(19):2079-86. (PubMed)
4. Vujic G, et al. Efficacy of orally applied probiotic capsules for bacterial vaginosis and other vaginal infections: a double- blind, randomized, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 2013;168(1):75-9. (PubMed)
5. Foxman B, et al. Prevalence of recurrent vulvovaginal candidiasis in 5 European countries and the United States: results from an internet panel survey. J Low Genit Tract Dis. 2013;17(3):340-5. (PubMed)
6. Corsello S, et al. An epidemiological survey of vulvovaginal candidiasis in Italy. Eur J Obstet Gynecol Reprod Biol. 2003;110(1):66-72. (PubMed)
7. Flores-Mireles AL, et al. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015;13(5):269-84.
8. Ceccarani C, et al. Diversity of vaginal microbiome and metabolome during genital infections. Sci Rep. 2019;9(1):14095. (PubMed)
9. Brubaker L, Wolfe A. The urinary microbiota: a paradigm shift for bladder disorders? Curr Opin Obstet Gynecol. 2016;28(5):407-12. (PubMed)