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NO Inducers* 180 Vegetarian Capsules

NO Inducers* 180 Vegetarian Capsules

$49.99

Nitric Oxide Support*

Targets arterial flexibility, endothelial function, and healthy blood flow with nutrients that support nitric oxide production.*

Category:
Beet

Description

Beet is a plant. The root and leaves are used as medicine. Beet root and leaves are also eaten as a vegetable.

People use beet most often for athletic performance. It is also used for liver diseases, reducing muscle soreness after exercise, high blood pressure, and other conditions, but there is no good scientific evidence to support these uses.

Effectiveness Header

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Possibly Effective

  • Athletic performance. Drinking beetroot juice might improve exercise performance during aerobic activities in some people. But it’s unclear how much or how often beetroot juice is needed for benefit. And any benefit in elite athletes might be too small to be meaningful.
  • Muscle soreness caused by exercise. Drinking beetroot juice a few times a day for about 48 hours after exercise may reduce muscle soreness after sprinting or jumping.

Insufficient Evidence

  • High blood pressure. Drinking beetroot juice might reduce blood pressure in some people. But it doesn’t seem to work in people with high blood pressure.
  • High levels of fats called triglycerides in the blood (hypertriglyceridemia). Taking a mixture of beet and hawthorn seems to reduce triglycerides by a small amount in people at risk of heart disease. But taking beet leaf doesn’t seem to reduce triglycerides.
  • Obesity. Taking beet leaf doesn’t seem to improve weight loss when taken for 4 weeks in people already given nutrition advice.
  • High blood pressure during pregnancy. Early research shows that taking beetroot juice doesn’t lower blood pressure in pregnant women with high blood pressure.
  • High blood pressure in arteries in the lungs (pulmonary hypertension). Early research shows that taking beetroot juice doesn’t lower blood pressure in the lungs of people with pulmonary hypertension.
  • Liver disease.
  • Other conditions.

Action

Beets contain chemicals that might reduce swelling and cholesterol. Also, beet can increase levels of a chemical called nitric oxide in the body. Nitric oxide can affect blood vessels, possibly reducing blood pressure and making it easier to exercise.

Safety

When taken by mouth: Beet is LIKELY SAFE for most people when taken in the amounts typically found in foods. Beet is POSSIBLY SAFE for most people when taken by mouth in medicinal amounts.

Beet can make urine or stools appear pink or red. But this is not harmful. There is concern that beets might cause low calcium levels and kidney damage. But this hasn’t been shown in people.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn’t enough reliable information to know if beet is safe to use as a medicine when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Kidney disease: Eating too many beets might make kidney disease worse.

Drug Interactions

There are no known interactions with medications. Before taking this product, talk with your health professional if you take any medications.

Herb Interactions

There are no known interactions with herbs and supplements.

Food Interactions

There are no known interactions with foods.

Dosage

The following doses have been studied in scientific research:

BY MOUTH:

  • For athletic performance: Beetroot juice 70-140 mL daily has been used, often taken a few hours before exercise. Baked beetroot 200 grams taken 75 minutes before exercise has also been used. Beetroot concentrate 50 mg twice daily for about 6 days has been used.
  • For muscle soreness caused by exercise: Beetroot juice (Love Beets Beetroot Juice) 125 or 250 mL per serving has been used for a total of 7-8 servings over approximately 2 days following exercise.

Other Names

Beet Greens, Beet Juice, Beet Leaves, Beetroot, Beetroot Juice, Beta vulgaris, Betarraga, Beets, Betterave, Betterave à Sucre, Betterave Jaune, Betterave Rouge, Betteraves, Fodder Beet, Garden Beet, Green Beet, Mangel, Mangold, Red Beet, Remolacha, Scandinavian Beet, Sugarbeet, Yellow Beet.

Disclaimer

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.

© Copyright 1995-2020. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber’s Letter, and Pharmacist’s Letter. All rights reserved.

Propionyl-L-Carnitine

Description

Propionyl-L-carnitine is a chemical. It is made in the body. Propionyl-L-carnitine is related to two other compounds called L-carnitine and acetyl-L-carnitine.

People use propionyl-L-carnitine for leg pain during exercise due to poor blood flow (intermittent claudication), congestive heart failure (CHF), chest pain (angina), low levels of testosterone in older men, inflammatory bowel disease (including Crohn disease and ulcerative colitis), and many other conditions, but there is no good scientific evidence to support most of these uses.

Effectiveness Header

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Possibly Effective

  • Low levels of testosterone in older men. Taking propionyl-L-carnitine by mouth in combination with acetyl-L-carnitine for six months seems to improve sexual performance, depression, and tiredness in older men. Taking this combination seems to work about as well as taking the chemical testosterone.
  • Chest pain (angina). Taking propionyl-L-carnitine by mouth seems to help people with angina walk farther. In some people, it might reduce how often they feel chest pain.
  • Heart disease. When given with a needle in the vein, propionyl-L-carnitine helps the heart pump better in people with ischemic heart disease.
  • Heart failure and fluid build up in the body (congestive heart failure or CHF). Taking propionyl-L-carnitine seems to improve how the heart works in people with mild or moderate CHF. It also seems to help people with this disease walk farther.
  • Erectile dysfunction (ED). Taking propionyl-L-carnitine along with sildenafil (Viagra) may work better than taking sildenafil alone in men with diabetes and ED. Also, taking a specific product that contains propionyl-L-carnitine and other ingredients seems to help with sexual performance in men with ED.
  • Leg pain during exercise due to poor blood flow (intermittent claudication). Propionyl-L-carnitine taken by mouth or given with a needle in the vein seems to help people with leg pain walk farther than they otherwise could. Propionyl-L-carnitine seems to work best for people with more severe disease.
  • A disease that causes curved, painful erections (Peyronie disease). The combination of propionyl-L-carnitine and injection of a medication called verapamil seems to improve sexual performance, slow down worsening of the disease, and possibly prevent surgery in people with Peyronie’s disease.
  • A type of inflammatory bowel disease (ulcerative colitis). Propionyl-L-carnitine might reduce symptoms in people with ulcerative colitis who are also using other medications. It might even help them go into remission, which means that the symptoms go away.

Insufficient Evidence

  • Athletic performance. Taking a specific ingredient called glycine propionyl-L-carnitine might increase cycling strength. But taking too much glycine propionyl-L-carnitine or taking it too often might make exercise harder.
  • A type of inflammatory bowel disease (Crohn disease). Early research suggests that using propionyl-L-carnitine reduces symptoms in people with Crohn’s disease.
  • Chronic fatigue syndrome (CFS). Developing research suggests that propionyl-L-carnitine might improve general tiredness in patients with CFS. Interestingly, the combination of propionyl-L-carnitine and acetyl-L-carnitine appears to be less effective than either supplement alone.
  • Male-pattern baldness (androgenic alopecia).
  • Circulatory problems caused by diabetes.
  • Other conditions.

More evidence is needed to rate the effectiveness of propionyl-L-carnitine for these uses.

Action

Propionyl-L-carnitine helps the body produce energy. It is important for heart function, muscle movement, and many other body processes. It also seems to help increase circulation.

Safety

When taken by mouth: Propionyl-L-carnitine is LIKELY SAFE for most people. It can cause stomach upset, vomiting, stomach pain, diarrhea, weakness, back pain, chest infections, and chest pain (angina). It can also cause a “fishy” smell of the urine, breath, and sweat.

When given by IV: Propionyl-L-carnitine is LIKELY SAFE for most people when given intravenously (by IV) by a healthcare professional.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn’t enough reliable information to know if propionyl-L-carnitine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Underactive thyroid (hypothyroidism): There is a concern that propionyl-L-carnitine might make hypothyroidism worse or thyroid hormone treatment less effective. This is because a related chemical, L-carnitine, seems to interfere with thyroid hormone. If you have hypothyroidism, don’t take propionyl-L-carnitine.

Seizures: Some people who have a history of seizures have reported an increase in the number and severity of seizures after taking L-carnitine by mouth or when given with a needle in the vein (by IV). There is a concern that this might also occur with propionyl-L-carnitine, because it is a similar chemical.

Drug Interactions

Acenocoumarol (Sintrom)

Interaction Rating=Moderate Be cautious with this combination.

Acenocoumarol (Sintrom) is used to slow blood clotting. Propionyl-L-carnitine might increase the effects of acenocoumarol (Sintrom). Increasing the effects of acenocoumarol (Sintrom) might slow blood clotting too much and cause bruising and bleeding. The dose of your acenocoumarol (Sintrom) might need to be changed.

Warfarin (Coumadin)

Interaction Rating=Moderate Be cautious with this combination.

Warfarin (Coumadin) is used to slow blood clotting. Propionyl-L-carnitine might increase the effects of warfarin (Coumadin) and increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

Herb Interactions

D-carnitine: D-carnitine might interfere with the way the body processes L-carnitine, which is a “parent” chemical for propionyl-L-carnitine. There is a concern that supplemental D-carnitine might cause the levels of propionyl-L-carnitine to drop too low.

Food Interactions

There are no known interactions with foods.

Dosage

The following doses have been studied in scientific research:

BY MOUTH:

  • For heart disease: 500-2000 mg propionyl-L-carnitine twice daily.
  • For chest pain (angina): 500 mg propionyl-L-carnitine three times daily.
  • For low levels of testosterone in older men: 2 grams of propionyl-L-carnitine and 2 grams of acetyl-L-carnitine daily.
  • For erectile dysfunction (ED): 2 grams of propionyl-L-carnitine daily along with 50 mg of sildenafil (Viagra) given twice weekly. A specific combination of propionyl-L-carnitine 250 mg, niacin 20 mg, and arginine 2500 mg daily.
  • For a disease that causes curved, painful erections (Peyronie disease): 2 grams of propionyl-L-carnitine daily in combination with injections of a medication called verapamil.
  • For a type of inflammatory bowel disease (ulcerative colitis): 0.5-1 gram of propionyl-L-carnitine twice daily.

INTRAVENOUS:

  • For leg pain during exercise due to poor blood flow (intermittent claudication): Healthcare providers give propionyl-L-carnitine with a needle in the vein (by IV).

Other Names

3-propanoyloxy-4-(trimethylazaniumyl) butanoate, 3-(1oxo-propoxy)-4-trimethyl ammonium chloride) Butanoic Acid, Glycine Propionyl-L-Carnitine, Glycine Propionyl-L-Carnitine HCl, Glycine Propionyl-L-Carnitine Hydrochloride, L-carnitine Propionyl, LPC, PLC, Propionil-L-Carnitina, Propionyl-L-Carnitine Hydrochloride, Propionylcarnitine.

Disclaimer

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.

© Copyright 1995-2020. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber’s Letter, and Pharmacist’s Letter. All rights reserved.

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Ingredients

Supplement Facts
Serving Size3 capsules
Servings Per Container60
Amount per serving
Setria® Performance Blend: L-Citrulline (Kyowa Quality®), L-Glutathione (Reduced)1.1 g
Propionyl-L-Carnitine250 mg
L-Arginine125 mg
Taurine25 mg
Beet (Root) Powder250 mg
Other ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, silicon dioxide, L-leucine.

Setria Setria® is a registered trademark of Kyowa Hakko Bio Co., Ltd.
Suggested Use

Suggested Use: As a dietary supplement, 3 capsules two times daily with or without food, or as directed by a healthcare practitioner.

CAUTION: If pregnant or nursing, consult your healthcare practitioner before use. If taking nitrates or anti-hypertensive medications, use under the direct supervision of a qualified healthcare practitioner. Keep out of reach of children.

Variations in product color may occur. Keep in a cool, dry place, tightly capped.