Natranix

CLINICAL APPLICATIONS 

• Supports Respiratory Health 
• Provides Immune Support During Seasonal Challenges 
  

Natranix is an alcohol-free, great-tasting syrup formulated to support respiratory health and the immune system during seasonal challenges. The formula includes botanicals echinacea, thyme, sage, elderberry and anise. 

Overview The human immune system is a complex network of millions of immune cells, which act together to protect the body from constant exposure to outside invaders. Most of the time, the immune system does a great job of keeping people healthy, but during certain times of the year, the immune system may require additional support. Studies have shown key ingredients in Natranix to be especially supportive to the immune system, as they include compounds that support respiratory health and normal mucus production, offering immediate support for children and adult immune challenges. 

Echinacea† Research has shown echinacea to be beneficial for various aspects of respiratory health, including balancing microbial activity and cytokines.1 A review of placebo-controlled randomized trials of echinacea found benefits for early stage upper respiratory tract support.2 An herbal compound containing Echinacea angustifolia was found to enhance respiratory health by 77% among children, over a one month period.3 Another research group found an echinacea product offered dual action for microbial balance in the respiratory tract and helped maintain normal inflammatory balance.4 

Thyme† Thyme has a long history of use in natural medicine in connection with chest and respiratory support. The health supporting effects of Thymol, its primary volatile oil, are well- documented. Thyme and its extracts have been found to relax respiratory muscles5 and to possess microbial-balancing properties.6,7 Thyme has also been shown to help increase the transport of mucus by cilia (minute, hair-like structures in the lungs that help expel mucus out of the lungs).8 

Elderberry† Elderberry has been used for centuries to support respiratory health. Elderberry fruit preparations have been shown to provide antioxidant support and microbial balancing effects in vitro,9 and has been shown to have balancing effects across a broad range of microbial organisms.10 One randomized, double-blind, placebo-controlled study done in Norway, investigated the efficacy and safety of oral elderberry syrup among 60 patients aged 18-54 years, with upper respiratory symptoms for 48 hours or less. They received 15 ml of elderberry or placebo syrup four times a day for five days, and symptoms were recorded using a visual analogue scale. Elderberry boosted immune function and calmed respiratory challenges on an average of four days earlier than the placebo group.11 

Sage† Sage or (Salvia officinalis) is approved by the German Commission E for external use in supporting the mucous membranes of the mouth and throat.12,13 

Directions 1 teaspoon (5 mL) 3 times per day or as recommended by your health care professional. Not recommended for children under 1 year old. 

Botanical products may cause mild stomach upset or an allergic reaction. Move dose closer to meals or cease product if symptoms persist. 

Does Not Contain Gluten, corn, yeast, artificial colors and flavors. 

Cautions If you are pregnant or nursing, consult your physician before taking this product. 

References

1. Sharma M, Anderson SA, Schoop R, Hudson JB. Induction of multiple pro-inflammatory cytokines by respiratory viruses and reversal by standardized Echinacea, a potent antiviral herbal extract. Antiviral Res. 2009 Aug;83(2):165- 70. 

2. Barrett B, Vohmann M, Calabrese C. Echinacea for upper respiratory infection. J Fam Pract. 1999 Aug;48(8):628-35. 

3. Minetti AM, Forti S, Tassone G, Torretta S, Pignataro L. Efficacy of complex herbal compound of Echinacea angustifolia (Imoviral® Junior) in recurrent upper respiratory tract infections during pediatric age: preliminary results. Minerva Pediatr. 2011 Jun;63(3):177-82. 
4. Sharma SM, Anderson M, Schoop SR, Hudson JB. Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (Echinaforce): dual actions against respiratory bacteria. Phytomedicine 2010 Jul;17(8- 9):563-8. Epub 2009 Dec 29. 

5. Engelbertz J, Lechtenberg M, Studt L, Hensel A, Verspohl 
6. Bioassay-guided fractionation of a thymol-deprived hydrophilic thyme extract and its antispasmodic effect. J Ethnopharmacol. 2012 Jun 14;141(3):848-53. 
7. Sienkiewicz M, Łysakowska M, Ciećwierz J, Denys P, Kowalczyk E. Antibacterial activity of thyme and lavender essential oils. Med Chem. 2011 Nov;7(6):674-89. 

7. Sienkiewicz M, Łysakowska M, Denys P, Kowalczyk E. The antimicrobial activity of thyme essential oil against multidrug resistant clinical bacterial strains. Microb Drug Resist. 2012 Apr;18(2):137-48. Epub 2011 Nov 21. 

8. Begrow F, Engelbertz J, Feistel B, Lehnfeld R, Bauer K, Verspohl EJ. Impact of thymol in thyme extracts on their antispasmodic action and ciliary clearance. Planta Med. 2010 Mar;76(4):311-8. Epub 2009 Oct 6. 

9. Vlachojannis JE, Cameron M, Chrubasik S. A systematic review on the sambuci fructus effect and efficacy profiles. Phytother Res. 2010 Jan;24(1):1-8. 

10. Krawitz C, Mraheil MA, Stein M, Imirzalioglu C, Domann E, Pleschka S, Hain T. Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses. BMC Complement Altern Med. 2011 Feb 25;11:16. 

11. Zakay-Rones Z1, Thom E, Wollan T, Wadstein J. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. J Int Med Res. 2004 Mar-Apr;32(2):132-40. 

12. Bouajaj S, Benyamna A, Bouamama H, Romane A, Falconieri D, Piras A, Marongiu B. Antibacterial, allelopathic and antioxidant activities of essential oil of Salvia officinalis L. growing wild in the Atlas Mountains of Morocco. Nat Prod Res. 2013;27(18):1673-6. 

13. Stefanović OD1, Stanojević DD, Comić LR. Synergistic antibacterial activity of Salvia officinalis and Cichorium intybus extracts and antibiotics. Acta Pol Pharm. 2012 May- Jun;69(3):457-63.