Lipanase ™

Lipanase™, provided by Douglas Laboratories®, is a natural pancreatic enzyme supplement formula providing high strength pancreatin to provide complete digestive support for fats, carbohydrates and proteins. †

FUNCTIONS
Intestinal bloating, abdominal pain after eating, fullness or heaviness in your stomach, nausea, gas ? These are just some of the signs often encountered with poor digestion.  Illness such as SIBO, IBS‚  IBD, Leaky gut, stress‚ and changes in your diet can all affect your digestion leading to malabsorption of and nutritional deficiencies.

Problems with your pancreas can also lead to digestion problems‚ The pancreas supplies the major digestive enzymes that catalyze the breakdown of starches (carbohydrates), proteins, and fats, so that the breakdown products can be absorbed in the upper small intestine.

Amylases break down starches to maltose and maltotriose, which are further hydrolyzed into glucose by the disaccharidases of the mucosal cells, and then absorbed. Although cellulose is indigestible by pancreatic and intestinal enzymes, the microflora within the large intestine may degrade it and produce uncomfortable symptoms in the process.

Although fat digestion starts in the mouth with the action of salivary lipase, the great majority of fat triglycerides are digested by pancreatic lipase secreted by the exocrine pancreas into the duodenum. Lipases break down triglycerides into monoglycerides and free fatty acids, which are efficiently absorbed in the upper small intestine. In the small intestine, proteases break down these polypeptides into free amino acids, and di-and tripeptides, which are directly absorbed by the intestinal mucosa. Lipanase provides high levels of catalytically active pancreatic enzymes which are specific for fats, carbohydrates and proteins.

Lipanase provides three essential enzymes in this formula:

• Amylase‚ which may help change complex starches or carbohydrates into simple sugars.
• Lipase‚ which aids your body in processing or breaking down fats.
• Protease‚ which may help improve your body’s effectiveness at breaking down proteins.

INDICATIONS
Lipanase™ tablets may be a useful nutritional adjunct for individuals who wish to supplement their diets with
pancreatic lipase, protease and amylase.

Each tablet contains:
8X Pancreatin 8X………………………………………………300 mg
Equivalent to 2,400 mg Pancreatin USP which provides the following minimum enzyme activity:
Lipase…………………………………………………………………… 4,800 USP Units
Protease ……………………………………………………………….60,000 USP Units
Amylase………………………………………………………………..60,000 USP Units
Other ingredients: Celluose, vegetable sterine, magnesium sterate, silica, and pharmaceutical glaze.

SUGGESTED USE
Adults may take one or two tablets with each meal, and with food eaten between meals. Do not to exceed
seven tablets daily unless directed by a healthcare practitioner. Not intended for chewing. Do not take this
product if you are allergic to pork.

SIDE EFFECTS
No adverse side effects have been reported.

STORAGE
Store in a cool, dry place, away from direct light. Keep out of reach of children.

REFERENCES
Domínguez-Muñoz JE, et al. Aliment Pharmacol Ther. 2005 Apr 15;21(8):993-1000.
Perano SJ, et al. J Clin Endocrinol Metab. 2014 Jul;99(7):2486-93. doi:10.1210/jc.2013-4417.
Kahl S, et al. JOP. 2014 Mar 10;15(2):165-74. doi: 10.6092/1590-8577/797.
Nakamura S, Takami M, Tanabe K, Oku T. Int J Food Sci Nutr. 2014 Sep;65(6):754-60.
doi:10.3109/09637486.2014.908168.
Untersmayr E, Jensen-Jarolim E. Curr Opin Allergy Clin Immunol. 2006 Jun;6(3):214-9. Review.

† These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

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