Gastrointestinal anti-biofilm enzyme formulations for use under the direction of an appropriately trained healthcare professional
InterFase® is a potent enzyme formulation specifically designed to disrupt gastrointestinal biofilm communities. Although a normal survival mechanism for commensal bacteria, undesirable organisms may become entrenched in biofilm and therefore unresponsive to conventional and natural remedies including probiotics.
InterFase® enzymes have been selected for their ability to lyse foundational extracellular polymers as well as degrade bacterial and yeast cell walls. The addition of disodium ethylenendiaminetetraactic acid (EDTA) in InterFase® Plus delivers more aggressive anti-biofilm action by binding metals needed for biofilm formation.
InterFase® and InterFase® Plus are formulated to be employed as part of a comprehensive program to support GI health by modifying undesirable gut biofilm.
The products are designed to be used in conjunction with botanical, supplement, and/or conventional treatments. Also, changes in diet are usually necessary and the use of probiotics is strongly advised.
As part of a comprehensive program, they should always be used under the direction of an appropriately trained healthcare professional.
InterFase® Plus is not intended for long-term daily use. It is also contraindicated in individuals under 18 years of age, pregnant or nursing mothers, individuals with liver or kidney conditions, or other conditions as indicated by the dispensing healthcare professional.
- Bacteria attach to the lumen.
- Colonies of bacteria form via adhesins such as polysaccharides and components of bacterial membranes.
- Bacteria secrete molecules known as autoinducers, which at high concentrations induce expression of proteins that facilitate multi-cellprocesses such as biofilm development.
- Cell growth and continual secretion of polysaccharides result in expansion of the biofilm, with dying cells releasing DNA and proteins—further strengthening the matrix and adding layers to the biofilm.
- Biofilms are able to persist as they simply detach, disperse, and re-colonize elsewhere.
InterFase Plus® provides the same unique enzyme formulation as InterFase® with the addition of ethylenediaminetetraacetic acid (EDTA). The presence of calcium, iron, and magnesium is essential for biofilm creation and serves to cross-link the anionic regions for polymers.
InterFase Plus® includes ethylenediaminetetraacetic acid (EDTA) which binds the metals needed for biofilm formation.
Biofilm consists of microorganisms encased within a self-produced matrix of exopolysaccharides and exoproteins that strongly adheres to interfaces and resists dislodgement.
Microorganisms residing within biofilms are highly resistant to antimicrobials including antibiotics and bacteriocins produced by probiotics. InterFase Plus® is a unique enzyme formulation with EDTA that is especially designed to disrupt the biofilm matrix that embeds potential gastrointestinal pathogens.
Enzymes in InterFase Plus® are selected for their ability to lyse the extracellular polymers commonly found in biofilm as well as degrade bacterial and yeast cell wall structures.
The enzyme blend in InterFase Plus® was developed using in vitro testing of antibiofilm activity and was found to have significant antibiofilm activity resulting in meaningful degradation of biofilm communities of potentially pathogenic bacteria and yeast.
InterFase Plus® is intended for use in conjunction with efforts to support normal gastrointestinal function and microflora.
As an adjunct to other efforts to eliminate potential pathogens, it is best combined with use of a high-potency, broad, multispecies probiotic formulation and a prebiotic to encourage the formation of healthy intestinal microbial biofilm communities.
It may also be combined with antimicrobial agents. The capsules should be taken away from meals to maximize the enzyme effects.
Free of the following common allergens: milk/casein, fish, shellfish, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
This product is not intended for long-term daily use. Do not use this product if you are pregnant or nursing, have kidney or liver condition or are below the age of 18.
If you have any other medical condition, if you are taking prescription drugs, or are allergic to eggs, consult your healthcare professional before using this product. Keep out of reach of children.