DIM Estro

$45.90

DIM Estro™ supports healthy estrogen metabolism for men and women. DIM is an advanced metabolite of Indole-3-Carbinol, the indole found in cruciferous vegetables. Indoles support healthy estrogen metabolism and an optimal ratio of estrogen metabolites, including 2-hydroxyestrogen and 16-hydroxyestrogen. The BioPerine® and curcumin combination has been added to enhance the bioavailability, extent of absorption and serum concentration of the bioactive curcuminoids.

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DIM Estro™ supports healthy estrogen metabolism in men and women.* DIM is an advanced metabolite of Indole-3-Carbinol, the indole found in cruciferous vegetables. Indoles support healthy estrogen metabolism and an optimal ratio of estrogen metabolites, including 2-hydroxyestrogen and 16-hydroxyestrogen. The BioPerine® and curcumin combination has been added to enhance the bioavailability, extent of absorption and serum concentration of the bioactive curcuminoids.*

Estrogen plays a role in various body functions. However, high levels of estrogen can pose health risks, such as weight gain, thyroid dysfunction, breast or ovarian cancer, and blood clots. How can you get rid of excess estrogen you ask? The answer is supporting proper estrogen detoxification in the body. There are three phases of estrogen detox. The body metabolizes estrogen using two phases in the liver and then eliminates it in our stool.
Phase 1 Detoxification:
During the first phase of estrogen detox, metabolism can go one of three pathways:
-2-OH: ideally, 60-80% of estrogen goes down this pathway and is the most beneficial pathway since it has anti-cancer properties. ⁣⁣
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-4-OH: ideally, less than 10% goes down this pathway. This is the least desirable pathway since it can make reactive estrogen products that can potentially damage DNA. ⁣⁣
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-16-OH: ideally, 13-30% goes down this pathway. We don’t want too much estrogen going down this pathway since it can exacerbate high estrogen symptoms.
DIM and Estrogen metabolites
Phase 2 Liver Detoxification:
⁣⁣After phase 1, estrogen metabolism, 4-OH, and 2-OH estrogens are deactivated by methylation (different from MTHFR but still involves COMT). This is an essential step. Why? Because we need to neutralize estrogen so that the body can eliminate it. ⁣⁣
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I like to think of this as a bathtub (Dr. Carrie Jones gave this analogy at a conference I went to and I’ll never forget it!). ⁣⁣Phase 1 estrogen detox is like filling a bathtub. Once your bathtub is full, you have to drain it—there’s where phase 2 comes in. To drain the bathtub, your body uses methylation, amino acids (such as glycine and glutamine), magnesium, and SAM to support the enzyme COMT in turning your estrogen into a water-soluble compound. This allows the estrogen to be in a form that can easily be eliminated. If you do not drain your bathtub, the estrogen can recirculate and cause issues. ⁣⁣
⁣⁣Why is my body favoring a negative pathway?
⁣⁣
There are several reasons that you could be favoring a less desirable pathway: ⁣⁣
  • inflammation! if you have inflammation in the gut, poor digestion, etc. could impact this pathway. ⁣⁣
  • high fat, low fiber diets ⁣⁣(think keto and low carb)
  • environmental chemicals⁣⁣
  • nutrient deficiencies (especially b vitamins, vitamin c, and vitamin e)⁣⁣
  • genetic mutations⁣⁣
The DIM compound may have several estrogen-related effects in your body:
  • Helps prevent the effects of estrogen on cells.
  • Slows some cancer cells.
  • Lowers toxins produced by your body’s natural metabolism.
  • Boosts antioxidants.
  • Promotes weight loss.
  • Enhances memory.
  • Improves mood.
  • Reduces symptoms of PMS, Perimenopause Symptoms
  • Acne
  • Menopause Symptoms

What Does Estro DIM do?

EstroDIM provides the combined power of vegetable metabolites I3C and DIM in an easy-to-take capsule. These metabolites work together to support estrogen balance and breast and prostate health.

What Are The Benefits of DIM

Uses and potential benefits of DIM supplements. DIM supplements are being studied for their protective effects against certain cancers. They’re also used to help prevent prostate enlargement, treat acne, aid weight loss, and reduce premenstrual syndrome (PMS) and menopause symptoms.

When should I take DIM Estro?
Most people find that taking DIM in the morning with a glass of water and a little food is the best way to go. Some women who have insomnia related to estrogen dominance, perimenopause, or menopause find that taking DIM at night helps them stay asleep longer – and even through the night.
Does DIM clear estrogen?
Taking DIM in an absorbable formulation encourages active and healthy estrogen metabolism. DIM supports estrogen balance by increasing beneficial 2-hydroxy estrogens and reducing the unwanted 16-hydroxy variety. This improves estrogen metabolism and helps resolve all three forms of estrogen dominance.

Two Capsules Contain:
Curcumin (from turmeric) (Curcuma longa) (root) extract (95% pure curcuminoids)† 600 mg
Diindolylmethane (DIM) 150 mg
Black pepper (Piper nigrum) (fruit) extract (50:1) (95% piperine)‡ 2 mg

Other Ingredients: Hydroxypropyl methylcellulose (vegetable capsule), microcrystalline cellulose, silicon dioxide, magnesium stearate.

Does Not Contain:  Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.

Specifications:

Size 120 Vegetable Capsules

Serving Size 2 Capsules

Servings Per Container 60

Directions:

Take two capsules once per day or as directed by your healthcare practitioner.

Caution: If you are pregnant or nursing, consult your healthcare practitioner before use. Keep out of reach of children.

Storage: Keep tightly closed in a cool, dry place.

†Curcumin C3 Complex® is a registered trademark of Sabinsa Corp.

‡BioPerine® is a registered trademark of Sabinsa Corp.

BioPerine® and Curcumin C3 Complex® are GRAS affirmed & Non-GMO Project Verified ingredients.

Brand

Nu-Medica