- Calcium and magnesium extracts blended into one supplement
- Helps support bone mass‡
- Cardiovascular Support‡
- Created for optimal absorption
- Supports energy production ATP
- Made with hypoallergenic, vegan ingredients
Calcium Magnesium (malate) 2:1 combines di-calcium malate and di-magnesium malate to provide a powerful calcium and magnesium nutritional supplement to reduce risk of osteoporosis
Risk factors for osteoporosis include sex, race, age and inadequate calcium intake. Populations at highest risk for osteoporosis include Caucasian, Asian, postmenopausal women, and elderly women and men. Adequate calcium intake throughout life is linked to a reduced risk of osteoporosis, as calcium helps to optimize peak bone mass during adolescence and early adulthood in conjunction with exercise and healthy diet. Calcium intake greater than 2,000 mg per day has no further known benefit to bone health.
What Is It?
Calcium Magnesium (malate) 2:1 combines di-calcium malate and di-magnesium malate in a 2:1 ratio for the highest elemental calcium and magnesium per capsule. These minerals are fully chelated with Krebs cycle intermediate malate for optimal absorption.
Uses For Calcium Magnesium (malate) 2:1
Bone Support: Randomized, double blind, placebo- controlled studies have reported statistically significant benefits of calcium supplementation for bone health and osteoporosis support†.
Magnesium, like calcium, is an essential bone matrix mineral that promotes healthy bone metabolism. A trial involving 2,038 older individuals indicated that higher intakes of magnesium were positively associated with bone mineralization for certain individuals. Supplementation with calcium and magnesium provides synergistic support for bone health.*
†Risk factors for osteoporosis include sex, race, age and inadequate calcium intake. Populations at highest risk for osteoporosis include Caucasian, Asian, postmenopausal women, and elderly women and men. Adequate calcium intake throughout life is linked to a reduced risk of osteoporosis, as calcium helps to optimize peak bone mass during adolescence and early adulthood in conjunction with exercise and healthy diet. Calcium intake greater than 2,000 mg per day has no further known benefit to bone health.
Cardiovascular Support: Magnesium supports cardio- vascular health by helping to maintain healthy levels of cellular and plasma electrolytes, including calcium and potassium. Calcium also promotes healthy receptor function. Additionally, calcium and magnesium may help to promote healthy lipid metabolism.*
Kreb cycle Support– Magnesium malate also offers the benefits of malic acid, such as the support of cellular energy production (Krebs Cycle) and the chelation of heavy metals such as aluminum.
Magnesium’s most important function is the creation of energy in the trillions of cells making up our body. Magnesium is a cofactor in the production of ATP (adenosine triphosphate) via ATP synthase.
ATP is manufactured in the mitochondria and it must be bound to a magnesium ion (MgATP) in order to be biologically active.
There are 1,000-2,000 mitochondria in each human cell and ATP is made in each one through a series of 8 steps called the Krebs cycle. What’s remarkable about magnesium is that it is indispensable in 6 of those 8 steps.
We think of the Krebs cycle as a pathway for the breakdown of glucose but it takes pyruvate from the glycolysis cycle and makes ATP energy molecules.
The Krebs cycle is also necessary for the breakdown of all metabolites: sugars, amino acids and fatty acids. Each of these groups of molecules has a pathway that leads into the Krebs cycle.
In addition, intermediates from the Krebs cycle can go the other direction and be used to synthesize amino acids and fatty acids. With the help of magnesium, the Krebs cycle in the mitochondria is our basic life force.
What Is The Source?
Calcium, magnesium and boron are derived from the lime of rock. Malate is synthetic. Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil.
DimaCal® is a registered trademark of Albion Laboratories, Inc. Malates covered by U.S. Patent 6,706,904 and patents pending.
Pure Encapsulations recommends 3-7 capsules per day, in divided doses, with or between meals.
Are There Any Potential Side Effects Or Precautions?
High doses of magnesium can cause loose stools. If pregnant or lactating, or have a history of kidney stones, consult your physician before taking this product.
Are There Any Potential Drug Interactions?
Calcium should be taken separately from certain antibiotics and thyroid medications. Calcium and magnesium should be taken separately from bisphosphonate medications. Consult your physician for more information.
Calcium Magnesium (malate) 2:1
Manufacturers of Hypo-allergenic Nutritional Supplements
Calcium Magnesium (malate) 2:1
each vegetable capsule contains v 00
calcium (as DimaCal® di-calcium malate)…………………………………
130 mg magnesium (as di-magnesium malate) ……………………………………..
65 mg ascorbyl palmitate (fat-soluble vitamin C) ………………………………… 10 mg
3–7 capsules per day, in divided doses, with or between meals.